Primary Antibody Matched Pairs
Biotium CD79b (B-Cell Marker)(IGB/1843), CF640R conjugate, 0.1mg/mL
CD79 (also designated Ig chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Bioss KD-Validated MAPK10 Rabbit Rec
Mitogen-Activated Protein Kinase 10 Primary Antibody Unconjugated Public Immunogen Range 1-36/274 Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB FCM IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
Meso Scale Discovery U-PLEX Human NGAL/LCN2 ASYQP
The Meso Scale Discovery U-PLEX Human NGAL (Lipocalin-2) Assay is an electrochemiluminescent immunoassay for the quantitative measurement of human neutrophil gelatinase-associated lipocalin (NGAL) in serum plasma urine cell culture supernatants and other biological samples This assay utilizes MSD s proprietary U-PLEX technology is highly sensitive has a broad dynamic range of 15 6-2000 pg/mL and shows no cross-reactivity with other human lipocalins The assay requires a small sample volume of 50 L and provides results in under 3 hours This product can aid in the study of acute kidney injury and other inflammatory conditions where NGAL is upregulated
AdipoGen IL-36beta (human) Matched Pair Detection Set (1 Set)
Matched Pair Detection Set. Detects human IL-36beta in cell culture supernatant. Colorimetric assay. Sample Type: Cell Culture Supernatant. Range: 15.6 to 1000 pg/ml. Sensitivity: 10 pg/ml. IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.
Medchemexpress LLC IGF2BP2 Human T7-H 50ug
Recombinant human IGF2BP2 protein (residues M1-T220) supplied as a lyophilized powder. Expressed in E. coli with an N-terminal T7 tag and a C-terminal 6xHis tag, the protein is intended for biochemical assays, antibody validation, and binding studies. Purity is ≥96% by reducing SDS-PAGE and the approximate molecular weight is 31.0 kDa.
- Lyophilized recombinant protein format for long-term storage.
- Contains N-terminal T7 and C-terminal 6xHis affinity tags for detection and purification.
- Sequence corresponds to human IGF2BP2 residues M1-T220 (accession Q9Y6M1-2).
- Purity ≥96% as determined by reducing SDS-PAGE.
- Recommended reconstitution at ≥100 μg/mL in ddH2O; aliquot and freeze at -20°C or -80°C for extended storage.
- Approximate molecular weight 31.0 kDa.
- Suitable for biochemical assays, antibody validation, and binding studies.
Human VEGFA ELISA Pair Set 15PP (Sino Biological)
Each vial contains 28 ng of recombinant Human VEGF165/VEGFA. Reconstitute with 1 mL dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in dilution buffer, and a high standard of 1200 pg/mL is recommended.
Biotium Thymidylate Synthase (5-FU Resistance Marker) (TYMS/1884), CF647 conjugate, 0.1mg/mL
This antibody recognizes a protein of 36 kDa, identified as Thymidylate Synthase (TS) (EC 2.1.1.45). It converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein has been reported to associate with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not r
Biotium Granzyme B (NK/T-Cell Lymphoma Marker)(GZMB/3055), Biotin conjugate, 0.1mg/mL
Granzyme B is a member of the granule serine protease family stored specifically in NK cells or cytotoxic T cells. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. Granzyme B is crucial for the rapid induction of target cell apoptosis by CTLs in the cell-mediated immune response. Granzyme B is useful as a marker in the identification of NK/T-cell lymphomas. High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in Hodgkin's Disease. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommende
Biotium CD79b (B-Cell Marker)(B29/123), CF568 conjugate, 0.1mg/mL
CD79 (also designated Ig chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Medchemexpress LLC COASY Human His 100ug | 100ug
COASY protein is a bifunctional enzyme that plays a key role in catalyzing the fourth and fifth steps of the CoA biosynthetic pathway The coaD domain promotes the phosphopantothenate adenylyltransferase activity of the fourth reaction and the coaE domain drives the dephosphoCoA kinase activity of the fifth reaction COASY Protein Human (His) is the recombinant human-derived COASY protein expressed by E coli with N-His labeled tag
Sino Biological Recombinant Human NCAM-1/CD56 Protein (Site-Specific PE Conjugation, His Tag) 25 Tests
A DNA sequence encoding the human NCAM1 (NP_001070150.1) (Met 1-Pro 603) was expressed with a C-terminal polyhistidine tag. The protein is site-specifically conjugated with PE (Excitation= 495 - 566 nm, Emission Max.= 575 nm).
Sino Biological Recombinant Human RIOK1 Protein (Full length, GST Tag), Active 500 µg
Recombinant full-length human RIOK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Biotium S100A9(S100A9/1075), CF594 conjugate, 0.1mg/mL
This MAb stains the cytoplasm of macrophages and histiocytes in hematopoietic organs, Kupffer's cells of the liver and Langerhan's cells of the skin. It also stains the mantle zone B-lymphocytes of the lymph node and spleen, spermatogonia, and chief cells of the stomach. S100A9 is expressed by macrophages in acutely inflamed tissues and in chronic inflammation. It is detected in peripheral blood leukocytes, in neutrophils and granulocytes. It is present at sites of vascular inflammation. S100A9 is also expressed in epithelial cells constitutively or induced during dermatoses. S100A9 is a Calcium-binding protein. It has antimicrobial activity towards bacteria and fungi. It is important for resistance to invasion by pathogenic bacteria. It up-regulates transcription of genes that are under the control of NF-kappa-B. S100A9 plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). It promotes tubulin polymerization when unphosphorylate
ABclonal Technology CD209 Rabbit pAb
This gene encodes a C-type lectin involved in cell adhesion and pathogen recognition. It recognizes a wide range of pathogens, including mycobacteria causing leprosy and tuberculosis, viruses like Ebola, hepatitis C, HIV-1, Dengue, and SARS-CoV. The protein has four domains: a carbohydrate recognition domain, a flexible neck domain, a transmembrane region, and a cytoplasmic domain for internalization. It is closely related to CLEC4M (L-SIGN), differing in viral recognition and expression. This gene is highly expressed on dendritic cells. Polymorphisms in the neck region are linked to HIV-1 protection, and SNPs in the promoter affect susceptibility and severity of infectious diseases, such as the rs4804803 SNP associated with SARS severity.
Cusabio Technology LLC DOG IL1RN ELISA KIT
This kit detects IL1RN (Interleukin-1 receptor antagonist protein) in dogs designed for quantitative measurement in serum plasma and tissue homogenates Utilizing a sandwich ELISA method it offers a detection range of 15 6 pg/ml to 1000 pg/ml with a sensitivity of 3 9 pg/ml ensuring precise measurement of low-abundance samples The assay requires a short incubation period of 1-5 hours and uses a modest sample volume of 50-100 l per test Absorbance is measured at 450 nm for result analysis providing reliable and reproducible data Ideal for research applications requiring IL1RN level assessment this kit combines high sensitivity with streamlined protocols to support studies in immunology and inflammatory response monitoring